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| The core of purchasing Span (sorbitol fatty acid esters, SPAN) is to first determine the grade according to the purpose (food/pharmaceutical/industrial) ¡ú select the model according to the system (HLB value) ¡ú check the qualifications and physical and chemical indicators ¡ú test the stability of the batch. Here is a complete and directly implementable purchasing guide. 1¡¢ First, clarify: purpose and level (the most crucial first step) Sipan is divided into industrial grade, food grade, and pharmaceutical grade, with significant differences in compliance and pricing. 1. Food grade (must be given priority) Applicable: Food Emulsification (Ice Cream, Cream, Chocolate, Bread, Beverages) Mandatory qualifications: SC production license, GB national standard (such as GB 1886.41), ISO22000, third-party testing report Strict control indicators: acid value, saponification value, moisture, heavy metals (Pb, As), free fatty acids, peroxide value, National Health Commission of the People's Republic of China 2. Pharmaceutical grade (excipient grade) Applicable: Drug emulsification, solubilization, ointment, injection solution Mandatory qualifications: Pharmacopoeia standards (CP/USP/EP), registration of pharmaceutical excipients, CMA/CNAS reports, endotoxin qualification 3. Industrial/cosmetic grade Applicable: pesticides, coatings, textiles, cosmetics, lubricants, plastic anti fog drops Qualifications: ISO9001, enterprise standards; Cosmetics must comply with the safety technical specifications for cosmetics 2¡¢ Model selection by system: HLB value and application comparison table The core difference between Si Pan lies in the type of fatty acid and HLB value (hydrophilic lipophilic balance), which determines the emulsification type (W/O water in oil as the main factor). table Model Chemical Name HLB Appearance (25 ¡æ) Typical Application Sipan 20 monolaurate 8.6 amber liquid with low viscosity emulsification, wetting, and dispersion; Food/Cosmetics/Textiles Sipan 40 monopalmitate 6.7 micro yellow wax solid melting point system, food/cosmetics/ink Sipan 60 Monostearate 4.7 Micro Yellow Wax Solid Food Mainstream: Cream, Ice Cream, Bread, Chocolate Sipan 65 tristearate ester 2.1 yellow waxy solid thickens, stabilizes, and prevents fog droplets Sipan 80 monooleate 4.3 amber oily liquid universal ace: food, medicine, pesticide, coating, mechanical lubrication Sipan 85 trioleate ester 1.8 yellow oily liquid with strong oleophilicity, heavy load W/O emulsification, lubrication Selection mnemonic: Food Emulsification ¡ú Preferred Sipan 60/80 Doing medicine/low stimulation ¡ú Choose Si Pan 80/20 (medicinal grade) Strengthen oil affinity and high stability W/O ¡ú Choose Si Pan 85/65 To mix HLB with Tween tone ¡ú commonly used Span 80+Tween 80 3¡¢ Core Quality Indicators (Must See for Acceptance) 1. Physical and chemical indicators (qualified line) Acid value (mgKOH/g): Food grade ¡Ü 8; Pharmaceutical grade ¡Ü 7; Industrial ¡Ü 10 Saponification value: Corresponding range of model (e.g. Span 80:140-160) Hydroxyl value: corresponding range of model (deviation ¡Ü¡À 10%) Moisture content: ¡Ü 1.5% (liquid); ¡Ü 0.5% (solid) Color and odor: liquid amber color, solid slightly yellow; No rancid odor, National Health Commission of the People's Republic of China 2. Safety indicators (food/medicine) Heavy metals: Pb ¡Ü 10mg/kg, As ¡Ü 3mg/kg, National Health Commission of the People's Republic of China Burning residue (pharmaceutical): ¡Ü 0.1% Microorganisms (food/cosmetics): Total bacterial count, mold, pathogenic bacteria qualified 4¡¢ Manufacturers and procurement points (avoiding pitfalls) Qualification verification (one vote veto) Food: Must have SC, GB national standards, and third-party CMA testing Medicine: Must have qualifications for pharmaceutical excipients, pharmacopoeia standards, and registration numbers Refusal: No qualifications, no testing, "three no small factories" Choose a large factory/professional factory Priority: Annual production capacity of 10000 tons, automated production line, batch stability Domestic mainstream: Warner Chemical, Guoli Chemical, Wenzhou Qingming, Heda (imported) Sample testing (mandatory) Testing: HLB, emulsion stability, cold and hot cycling, compatibility Food: Conduct shelf life, taste, and oil separation layer testing Batch and Supply Requirements: Consistency, traceability, and stable supply within the same batch Bulk: signing long-term agreements, quality assurance clauses, returns and exchanges for non-conforming products 5¡¢ Quick selection decision table (directly applicable) Food (cream/ice cream/bread) ¡ú Sipan 60 food grade Food (Beverages/Chocolate/Anti Frost) ¡ú Sipan 80 Food Grade Pharmaceutical (topical/oral/solubilization) ¡ú Sipan 80 pharmaceutical grade (USP/EP) Cosmetics (cream/W/O emulsion) ¡ú Sipan 60/80 cosmetic grade Pesticides/Coatings/Industrial Emulsification ¡ú Sipan 80 Industrial Grade Strong affinity for oil/high stability ¡ú Span 85 6¡¢ One sentence summary Grade according to usage (food/pharmaceutical/industrial) ¡ú Select model according to HLB (60/80 most commonly used) ¡ú Check qualifications+physical and chemical indicators ¡ú Sample+batch inspection. |
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