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Characteristics of using polyethylene glycol |
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Polyethylene glycol is FDA approved, non immunogenic, non-toxic, and often used in a wide range of biomedical applications, including drug delivery, bioconjugation, tissue engineering, and surface functionalization. Polyethylene glycol biocoupling, also known as polyethylene glycol conjugation, is the covalent coupling of drug targets such as proteins, polysaccharides, and oligonucleotides with polyethylene glycol to improve the pharmacokinetic properties of drugs. In drug delivery applications, polyethylene glycol can serve as a linker for antibody drug conjugates (ADCs) or as a surface coating for nanoparticles to enhance systemic administration. Polyethylene glycol hydrogel is a water swelling three-dimensional polymer, which has the characteristics of anti biodegradation and protein adhesion. PEG hydrogels are synthesized by cross-linking the reactive polyethylene glycol end groups, which are widely used in drug delivery and tissue engineering. |
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